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1

Biomarker discovery for kidney diseases by mass spectrometry

Toshimitsu Niwa

Journal:

Journal of Chromatography B

Year:

2008

Language:

english

File:

PDF, 103 KB

english, 2008

2

Recent progress in the analysis of uremic toxins by mass spectrometry

Toshimitsu Niwa

Journal:

Journal of Chromatography B

Year:

2009

Language:

english

File:

PDF, 537 KB

english, 2009

3

Evidence for non-enzymatic glycosylation of Escherichia coli chromosomal DNA

Roumyana Mironova, Toshimitsu Niwa, Yordan Handzhiyski, Angelina Sredovska, Ivan Ivanov

Journal:

Molecular Microbiology

Year:

2005

Language:

english

File:

PDF, 312 KB

english, 2005

4

Presence of tetrahydroisoquinoline and 2-methyl-tetrahydroquinoline in Parkinsonian and normal human brains

Toshimitsu Niwa, Naohito Takeda, Norio Kaneda, Yoshio Hashizume, Toshiharu Nagatsu

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 283 KB

english, 1987

5

Indoxyl Sulfate Enhances p53-TGF-� 1 -Smad3 Pathway in Proximal Tubular Cells

Shimizu, Hidehisa, Yisireyili, Maimaiti, Nishijima, Fuyuhiko, Niwa, Toshimitsu

Journal:

American Journal of Nephrology

Year:

2013

Language:

english

File:

PDF, 223 KB

english, 2013

6

Indoxyl sulfate upregulates renal expression of ICAM-1 via production of ROS and activation of NF-κB and p53 in proximal tubular cells

Shimizu, Hidehisa, Yisireyili, Maimaiti, Higashiyama, Yukihiro, Nishijima, Fuyuhiko, Niwa, Toshimitsu

Journal:

Year:

2013

Language:

english

File:

PDF, 393 KB

english, 2013

7

Indoxyl Sulfate-induced Vascular Calcification is mediated through Altered Notch Signaling Pathway in Vascular Smooth Muscle Cells

Yamaguchi, Kazutoshi, Yisireyili, Maimaiti, Goto, Sumie, Kato, Katsuhiro, Cheng, Xian Wu, Nakayama, Takayuki, Matsushita, Tadashi, Niwa, Toshimitsu, Murohara, Toyoaki, Takeshita, Kyosuke

Journal:

International Journal of Medical Sciences

Year:

2020

File:

PDF, 2.62 MB

2020

8

Accumulation of aberrant Y chromosomes in γ-ray–induced thymic lymphomas lacking p53

Daizen Chou, Jun Matsuki, Yuko Saitou, Shin-ichi Kosugi, Toshimitsu Shinbo, Fumitake Gejyo, Ohtsura Niwa, Ryo Kominami

Journal:

Molecular Carcinogenesis

Year:

1999

Language:

english

File:

PDF, 119 KB

english, 1999

9

Mass spectrometry in the search for uremic toxins

Toshimitsu Niwa

Journal:

Mass Spectrometry Reviews

Year:

1997

Language:

english

File:

PDF, 441 KB

english, 1997

10

Both fertilization promoting peptide and adenosine stimulate capacitation but inhibit spontaneous acrosome loss in ejaculated boar spermatozoa in vitro

Hiroaki Funahashi, Atsushi Asano, Toshimitsu Fujiwara, Takashi Nagai, Koji Niwa, Lynn R. Fraser

Journal:

Molecular Reproduction and Development

Year:

2000

Language:

english

File:

PDF, 235 KB

english, 2000

11

A novel mutation (E358K) in the α-galactosidase A gene detected in a Japanese family with Fabry disease

Dr. Takashi Miyazaki, Mitsuharu Kajita, Sachiko Ohmori, Naoki Mizutani, Toshimitsu Niwa, Yoshiharu Murata, Hisao Seo

Journal:

Year:

1998

Language:

english

File:

PDF, 177 KB

english, 1998

12

Mass spectrometry for the study of protein glycation in disease

Toshimitsu Niwa

Journal:

Mass Spectrometry Reviews

Year:

2006

Language:

english

File:

PDF, 192 KB

english, 2006

13

Editorial: Mass spectrometry for the study and diagnosis of human disease

Toshimitsu Niwa

Journal:

Mass Spectrometry Reviews

Year:

2006

Language:

english

File:

PDF, 25 KB

english, 2006

14

Update of uremic toxin research by mass spectrometry

Toshimitsu Niwa

Journal:

Mass Spectrometry Reviews

Year:

2011

Language:

english

File:

PDF, 845 KB

english, 2011

15

Fate of the glucose degradation products 3-deoxyglucosone and glyoxal during peritoneal dialysis

Andreas Tauer, Thorsten O. Bender, Erwin H. Fleischmann, Toshimitsu Niwa, Achim Jörres, Monika Pischetsrieder

Journal:

Molecular Nutrition & Food Research

Year:

2005

Language:

english

File:

PDF, 166 KB

english, 2005

16

Simultaneous Detection of Methylenetetrahydrofolate Reductase Gene Polymorphisms, C677T and A1298C, by Melting Curve Analysis with LightCycler

Sakurako Nakamura, Tsutomu Aoshima, Mayumi Ikeda, Yoshitaka Sekido, Kaoru Shimokata, Toshimitsu Niwa

Journal:

Analytical Biochemistry

Year:

2002

Language:

english

File:

PDF, 55 KB

english, 2002

17

Presence of N-methyldopamine in parkinsonian and normal human brains

Mitsuharu Kajita, Toshimitsu Niwa, Naohito Takeda, Hideo Yoshizumi, Akira Tatematsu, Kazuyoshi Watanabe, Toshiharu Nagatsu

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1993

Language:

english

File:

PDF, 533 KB

english, 1993

18

Analysis of polyols in uremic serum by liquid chromatography combined with atmospheric pressure chemical ionization mass spectrometry

Toshimitsu Niwa, Kazuhiko Tohyama, Yoshiaki Kato

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1993

Language:

english

File:

PDF, 457 KB

english, 1993

19

Analysis of urinary organic acids by liquid chromatography—atmospheric pressure chemical ionization mass spectrometry

Mitsuharu Kajita, Toshimitsu Niwa, Kazuyoshi Watanabe

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1993

Language:

english

File:

PDF, 469 KB

english, 1993

20

Endogenous synthesis of N-methylnorsalsolinol in rat brain during in vivo microdialysis with epinine

Mitsuharu Kajita, Toshimitsu Niwa, Wakako Maruyama, Daiichiro Nakahara, Naohito Takeda, Hideo Yoshizumi, Akira Tatematsu, Kazuyoshi Watanabe, Makoto Naoi, Toshiharu Nagatsu

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1994

Language:

english

File:

PDF, 469 KB

english, 1994

21

Detection of 1-phenyl-N-methyl-1,2,3,4-tetrahydroisoquinoline and 1-phenyl-1,2,3,4-tetrahydroisoquinoline in human brain by gas chromatography—tandem mass spectrometry

Mitsuharu Kajita, Toshimitsu Niwa, Makoto Fujisaki, Makoto Ueki, Koichi Niimura, Mitsuhiko Sato, Kyoko Egami, Makoto Naoi, Mitsuo Yoshida, Toshiharu Nagatsu

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1995

Language:

english

File:

PDF, 359 KB

english, 1995

22

Liquid chromatographic-atmospheric pressure chemical ionization mass spectrometric analysis of glycine conjugates and urinary isovalerylglycine in isovaleric acidemia

Tetsuya Ito, Kiyoshi Kidouchi, Naruji Sugiyama, Mitsuharu Kajita, Taku Chiba, Toshimitsu Niwa, Yoshiro Wada

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1995

Language:

english

File:

PDF, 379 KB

english, 1995

23

Preface

Osamu Suzuki, Toshimitsu Niwa, Tohru Kojima

Journal:

Journal of Chromatography B

Year:

2004

Language:

english

File:

PDF, 23 KB

english, 2004

24

Preface

Seiji Yamaguchi, Toshimitsu Niwa, Akira Shimizu

Journal:

Journal of Chromatography B

Year:

2005

Language:

english

File:

PDF, 32 KB

english, 2005

25

Preface

Yoshinao Wada, Toshimitsu Niwa, Akira Shimizu

Journal:

Journal of Chromatography B

Year:

2006

Language:

english

File:

PDF, 71 KB

english, 2006

26

Protein glutathionylation and oxidative stress

Toshimitsu Niwa

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 203 KB

english, 2007

27

New challenge of mass spectrometry technique

Toshimitsu Niwa, Akira Shimizu

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 119 KB

english, 2007

28

Preface

Yosuke Shigematsu, Toshimitsu Niwa, Akira Shimizu

Journal:

Journal of Chromatography B

Year:

2008

Language:

english

File:

PDF, 110 KB

english, 2008

29

Metabolomic analysis of uremic toxins by liquid chromatography/electrospray ionization-tandem mass spectrometry

Kaori Kikuchi, Yoshiharu Itoh, Ryoko Tateoka, Atsuko Ezawa, Kenjiro Murakami, Toshimitsu Niwa

Journal:

Journal of Chromatography B

Year:

2010

Language:

english

File:

PDF, 679 KB

english, 2010

30

Metabolomic search for uremic toxins as indicators of the effect of an oral sorbent AST-120 by liquid chromatography/tandem mass spectrometry

Kaori Kikuchi, Yoshiharu Itoh, Ryoko Tateoka, Atsuko Ezawa, Kenjiro Murakami, Toshimitsu Niwa

Journal:

Journal of Chromatography B

Year:

2010

Language:

english

File:

PDF, 469 KB

english, 2010

31

Migration of tetrahydroisoquinoline, a possible parkinsonian neurotoxin, into monkey brain from blood as proved by gas chromatography—mass spectrometry

Toshimitsu Niwa, Naohito Takeda, Akira Tatematsu, Sadao Matsuura, Mitsuo Yoshida, Toshiharu Nagatsu

Journal:

Journal of Chromatography A

Year:

1988

Language:

english

File:

PDF, 417 KB

english, 1988

32

Analysis of glutathionyl hemoglobin levels in diabetic patients by electrospray ionization liquid chromatography–mass spectrometry: effect of vitamin E administration

Chika Naito, Toshimitsu Niwa

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2000

Language:

english

File:

PDF, 80 KB

english, 2000

33

Gas chromatographic—mass spectrometric profile of organic acids in urine and serum of diabetic ketotic patients

Toshimitsu Niwa, Kenji Maeda, Toyokazu Ohki, Akira Saito, Isamu Tsuchida

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1981

Language:

english

File:

PDF, 553 KB

english, 1981

34

Identification of 2-hydroxy-2-methyllevulinic acid in urine and serum of diabetic patients with ketoacidosis

Toshimitsu Niwa, Kenji Maeda, Toyokazu Ohki, Jinsaku Sakakibara

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1982

Language:

english

File:

PDF, 460 KB

english, 1982

35

Metabolic profiling with gas chromatography—mass spectrometry and its application to clinical medicine

Toshimitsu Niwa

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1986

Language:

english

File:

PDF, 2.61 MB

english, 1986

36

Gas chromatographic—mass spectrometric analysis of organic acids in renal tissue biopsy : Identification of 4-hydroxybutyric acid and 4-hydroxy-2-butenoic acid

Toshimitsu Niwa, Kenji Maeda, Hiroaki Asada, Masao Shibata, Toyokazu Ohki, Akira Saito, Hiroshi Furukawa

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1982

Language:

english

File:

PDF, 376 KB

english, 1982

37

Endogenous synthesis of N-methyl-1,2,3,4-tetrahydroisoquinoline, a precursor of N-methylisoquinolinium ion, in the brains of primates with parkinsonism after systemic administration of 1,2,3,4-tetrahydroisoquinoline

Toshimitsu Niwa, Hideo Yoshizumi, Akira Tatematsu, Sadao Matsuura, Mitsuo Yoshida, Minami Kawachi, Makoto Naoi, Toshihar Nagatsu

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1990

Language:

english

File:

PDF, 413 KB

english, 1990

38

Presence of tetrahydroisoquinoline, a parkinsonism-related compound, in foods

Toshimitsu Niwa, Hideo Yoshizumi, Akira Tatematsu, Sadao Matsuura, Toshiharu Nagatsu

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1989

Language:

english

File:

PDF, 347 KB

english, 1989

39

Detection of tetrahydroisoquinoline in parkinsonian brain as an endogenous amine by use of gas chromatography-mass spectrometry

Toshimitsu Niwa, Naohito Takeda, Toshikuni Sasaoka, Norio Kaneda, Yoshio Hashizume, Hideo Yoshizumi, Akira Tatematsu, Toshiharu Nagatsu

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1989

Language:

english

File:

PDF, 438 KB

english, 1989

40

Ischemic change of organic acids in kidney

Toshimitsu Niwa, Naoya Yamamoto, Hiroaki Asada, Atsuko Kawanishi, Masafumi Yokoyama, Kenji Maeda, Toyokazu Ohki

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1983

Language:

english

File:

PDF, 416 KB

english, 1983

41

Molecular heterogeneity of amyloid β2-microglobulin and modification with advanced glycation end products

Roumyana Mironova, Toshimitsu Niwa

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2001

Language:

english

File:

PDF, 197 KB

english, 2001

42

Determination of glutathionyl hemoglobin in hemodialysis patients using electrospray ionization liquid chromatography–mass spectrometry

Chika Naito, Mitsuharu Kajita, Toshimitsu Niwa

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1999

Language:

english

File:

PDF, 87 KB

english, 1999

43

Gas chromatographic–mass spectrometric analysis of erythrocyte 3-deoxyglucosone in hemodialysis patients

Saori Tsukushi, Kaoru Shimokata, Toshimitsu Niwa

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1999

Language:

english

File:

PDF, 186 KB

english, 1999

44

Erratum to the special issue of the Japanese Society for Biomedical Mass Spectrometry [J. Chromatogr. B, 731 (1999)]

Tomiko Kuhara, Toshimitsu Niwa, Isamu Matsumoto

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1999

File:

PDF, 22 KB

1999

45

Evidence for non-enzymatic glycosylation in Escherichia coli

Roumyana Mironova, Toshimitsu Niwa, Hideki Hayashi, Rositsa Dimitrova, Ivan Ivanov

Journal:

Molecular Microbiology

Year:

2001

Language:

english

File:

PDF, 371 KB

english, 2001

46

Nonylphenol induces the death of neural stem cells due to activation of the caspase cascade and regulation of the cell cycle

Chiho Kudo, Koichiro Wada, Tomotake Masuda, Toshimitsu Yonemura, Atsuhito Shibuya, Yohko Fujimoto, Atsushi Nakajima, Hitoshi Niwa, Yoshinori Kamisaki

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 221 KB

english, 2004

47

RNA metabolism in uremic patients: Accumulation of modified ribonucleosides in uremic serum Technical Note

Niwa, Toshimitsu, Takeda, Naohito, Yoshizumi, Hideo

Journal:

Kidney International

Year:

1998

Language:

english

File:

PDF, 225 KB

english, 1998

48

Increased erythrocyte 3-DG and AGEs in diabetic hemodialysis patients: Role of the polyol pathway

Tsukushi, Saori, Katsuzaki, Tomoyuki, Aoyama, Isao, Takayama, Fumio, Miyazaki, Takashi, Shimokata, Kaoru, Niwa, Toshimitsu

Journal:

Kidney International

Year:

1999

Language:

english

File:

PDF, 409 KB

english, 1999

49

Oral adsorbent ameliorates renal TGF-β1 expression in hypercholesterolemic rats

Aoyama, Isao, Miyazaki, Takashi, Takayama, Fumio, Tsukushi, Saori, Saga, Shinsuke, Shimokata, Kaoru, Niwa, Toshimitsu

Journal:

Kidney International

Year:

1999

Language:

english

File:

PDF, 325 KB

english, 1999

50

3-Deoxyglucosone and AGEs in uremic complications: Inactivation of glutathione peroxidase by 3-deoxyglucosone

Niwa, Toshimitsu, Tsukushi, Saori

Journal:

Kidney International

Year:

2001

File:

PDF, 881 KB

2001